Benefits of MPACT in Locally Advanced Head and Neck Cancer Patients Undergoing Chemoradiotherapy

Inclusion Criteria: * Patients greater than or equal to 40 years old with AJCC (American Joint Committee on Cancer) stage II-IV head and neck squamous cell carcinoma who are beginning first-line non-surgical treatment with concurrent chemoradiotherapy (CCRT) and who are capable of understanding and adhering to the protocol requirements * Patients must be willing to comply with the study procedures and visits. Exclusion Criteria: * Active or symptomatic cardiopulmonary disease * Substantial dementia * Acute medical conditions, such as acute flare-up of joint condition or infection * Participants must not be actively receiving physical therapy in a relevant area, at the time of enrollment, or participating in intensive (30 min per day) aerobic program three times per week. * Patients are actively being treated for another cancer at the time of enrollment * Active or unstable metabolic conditions such as brittle diabetes or severe anemia * Alcohol intake less than 3 ounces per day * Hemiplegia or lower limb amputation * Significant orthopedic or musculoskeletal condition that does not allow weight bearing * Unable to maintain safe stance and walk, either with or without an assistive device