To investigate pleiotropic effects of ticagrelor in addition to its antiplatelet effects in type 2 diabetic patients with non-ST elevation acute coronary syndrome by measuring inflammatory markers, circulating number of endothelial progenitor cells, brachial artery endothelial function, and arterial stiffness.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
NONE
Enrollment
60
Ticagrelor 90mg twice daily for 5 weeks
Prasugrel 10mg once daily for 5 weeks
Korea University Anam Hospital
Seoul, South Korea
Changes in circulating number of endothelial progenitor cells
Time frame: Expected average of 5 weeks
Changes in brachial artery flow mediated dilation
Time frame: Expected average of 5 weeks
Composite measure of brachial-ankle pulse wave velocity, and augmentation index.
Time frame: Expected average of 5 weeks
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