The aim of this study is to evaluate the efficacy and tolerability of Lonquek which is a pegylated (long-acting) version of Filgrastim recombinant human G-CSF (G-CSF) in mobilizing sufficient number of stem cells for autologous stem cell transplantation in patients with lymphoma and multiple myeloma.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
24
Patients will be given a single fixed dose of Lonquek (Teva LTD), 12-mg subcutaneously.
Chaim Sheba Medical Center
Tel Litwinsky, Israel
RECRUITINGMobilisation success rate
Mobilisation success rate is defined as the mobilisation of a peripheral blood stem cell graft containing \>2x106 CD34+ cells/kg in ≤ 4 apheresis sessions.
Time frame: 4 weeks
engraftment after transplantation
Time until recovery of blood counts after transplantation
Time frame: 100 days
Safety
Number of participants with adverse events
Time frame: 100 days
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