The purpose of this study is to evaluate the disease burden of hospitalized patients with CAP and healthcare-associated pneumonia (HCAP) in real life of China .
In China, the data about current management of patients hospitalized with CAP in the real-life setting is not available,type of pneumonia, selection of initial antibiotic, time to clinical stability, antibiotic choice anf modification,clinical outcomes and costs remain unclear. In this study, we will collect comprehensive information on CAP and HCAP management patterns to evaluate the disease burden of hospitalized patients with CAP and HCAP in real life of China .to analyze microbiological characteristics,clinical manifestations,antibiotic regimens ,adherences to guidelines and effect on outcome in different groups of patients with CAP (\> and = 65 years, different comorbidities ,risk factors) ,to investigate microbiological characteristics,clinical manifestations,antibiotic regimens ,adherences to guidelines and effect on outcome in different groups of disease severity with CAP ,to provide the difference on microbiological characteristics,clinical manifestations,antibiotic regimens ,and outcome between patients with CAP and HCAP ,to understand the current situation of antibiotic regimen ,to evaluate influence of different antibiotic regimens on prognosis.
Study Type
OBSERVATIONAL
Enrollment
3,000
retrospective cohort study
China-Japan Friendship Hospital
Beijing, China
RECRUITINGtreatment failure at 72h after initiation of antibiotics
treatment failure was defined as a change of antibiotics due to worsening signs or symptoms associated with pneumonia
Time frame: Time from the first dose use of antibiotics to 72 hours
in-hospital treatment failure due to multiple causes
1)death in hospital;2)change of antibiotics due to worsening signs or symptoms of infection, 3) recurrence, defined as signs or symptoms of infection after completion of therapy requiring re-initiation of antibiotics
Time frame: Time from date of admission to discharge up to 1 week
Duration of intravenous antimicrobial therapy
Time from the first dose of intravenous antibiotics to date of stop of intravenous antibiotics ,participants will be followed for the duration of hospital stay
Time frame: 2 weeks
Hospital length of stay
Patients will be asked about hospitalization, date, Patients will be asked about hospitalization, date, participants will be asked about the time of admission and discharge
Time frame: 2 weeks
in-hospital mortality
Time from date of admission to date of discharge,participants will be followed for the duration of hospital stay
Time frame: 2 weeks
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