CIK in Treating Patients With Bladder Cancer

Inclusion Criteria: * Patients histologically confirmed carcinoma in of the bladder with urinary cytology; * Patients with staging I-III of Bladder Cancer; * Patients who had completed chemotherapy; * Patients who have a life expectancy of at least 12 weeks; * Eastern Cooperative Oncology Group (ECOG) performance status was 0-1; * The bone marrow functioned normally (WBC\>4.0×10\^9/L, Hb\>120 g/L, Platelet(PLT)\>100×10\^9/L); * The ECG results were normal, and the liver and kidney were functional. Exclusion Criteria: * Patients who had upper urinary tract disease (e.g., vesico-ureteral reflux or massive stones) that would make multiple transurethral procedures risk; * Patients who had urethral strictures that would prevent endoscopic procedures and repeated catheterization; * Patients who had prior or concurrent upper urinary tract tumors; * Patients who had distant metastases by imaging studies; * Patients with uncontrolled infection; underlying disease that was severe or life-threatening; * Patients who were lactating; * ECOG perform status ≥ 2; * Patients who are suffering from auto immune diseases or patients who need to accept glucocorticoid treatment; * Patients who are pregnant or nursing; * Patients with active tuberculosis (highly positive skin tests allowed if no active disease); * Patients with disease that would preclude general anesthesia; * Patients with active intractable or uncontrollable infection.