The aim of this study is to determine the efficacy of the usage of a probiobitc lozenge in patients with residual bleeding pockets of ≥ 5mm 3 months following scaling and rootplaning. Simultaneously the additional benefit of subgingival application of probiotics via oil drops will be investigated.
The aim of this study is to determine the efficacy of the usage of a probiobitc lozenge in patients with residual bleeding pockets of ≥ 5mm following scaling and rootplaning. Simultaneously the additional benefit of subgingival application of probiotics via oil drops will be investigated. Recruitment: This study will be a single centre (Department of Oral Health Sciences, University Hospitals Leuven), double blind, randomized, placebo controlled clinical trial with within each patient a split mouth design. The randomization (by means of a computer program) and double blind design are thought to minimize the bias of the investigator and patients. Selection of the study population: Adults, who consult at the department of Periodontology at the University Hospital Leuven, and who fit the inclusion criteria will be asked to participate in this study.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
40
UZLeuven
Leuven, Belgium
Pocket Probing Depth (PPD) at teeth with residual pockets
Time frame: 3-6 months
Recessions (REC) at teeth with residual pockets
Time frame: 3-6 months
Clinical Attachment Loss (CAL) at teeth with residual pockets
Time frame: 3-6 months
Plaque at teeth with residual pockets
Time frame: 3-6 months
Bleeding on Probing (BoP) at teeth with residual pockets
Time frame: 3-6 months
Overall PPD, REC, CAL
Time frame: 3-6 months
Microbial samples: deepest pocket, saliva, tongue
Time frame: 3-6 months
Full Mouth Plaque Score (FMPS) and Full Mouth Bleeding Score (FMBS)
Time frame: 3-6 months
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