Post-transplant Cancer Incidence and Survival in Patients With or Without Pre-transplant Cancer

Uppsala University2,370 enrolled

Overview

Patients with previous malignancies have increasingly been accepted for renal transplantation. However, post-transplant malignancy risk and survival rates of these patients are unknown. Our aim was to assess if previous malignancies pose an unnecessarily high risk of post-transplant malignant tumours and if the organs as a resource are too limited for investment in this patient group.

Study Type

OBSERVATIONAL

Enrollment

2,370

Conditions

Neoplasms Kidney Failure

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Kidney transplanted patients from January 1982 through December 2013 with or without a pre transplant cancer. Exclusion Criteria: * Simultaneous kidney+pancreas transplantation. * Islet cell transplanted patients * Undiagnosed malignancies at the time of transplantation * Death within a week after transplantation * First transplantation at another hospital

Locations (1)

Uppsala University, Department of Surgical Sciences, Section of Transplantation Surgery

Uppsala, Sweden

Outcomes

Primary Outcomes

Incidence of post-transplant cancer

Time frame: Up to 33 years starting in January 1982.

Secondary Outcomes

Patient survival

Time frame: Up to 33 years starting in January 1982.

Cancer-induced mortality

Time frame: Up to 33 years starting in January 1982.

Data from ClinicalTrials.gov

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