Knowing and Remembering: Cognitive and Neural Influences of Familiarity on Recognition Memory in Early Alzheimer's Disease

Inclusion Criteria: Volunteers (pilot phase) * Aged 25 - 75 * French native speakers * Right-handed * Education level equal or superior to primary school leaving certificate * Free from any medical or psychiatric condition that may impact cognition * Having given written informed consent Volunteers (experimental phase) * Aged 60 - 75 * French native speakers * Right-handed * Education level equal or superior to primary school leaving certificate * Free from any medical or psychiatric condition that may impact cognition * Having given written informed consent AD-MCI participants * Aged 60 - 75 * French native speakers * Right-handed * Education level equal or superior to primary school leaving certificate * Fulfilling criteria for " AD-MCI " (Albert et al., 2011) * Have been seen in a memory medical center or in Memory Resources and Research Medical Center for cognitive symptoms * Free from any medical or psychiatric condition that may impact cognition * Able to understand and consent * Having given written informed consent Exclusion Criteria: MRI contraindications (all participants) * Claustrophobia * Wearing of any metal implant such as: * Heart pacemaker * Iron-magnetic surgical clips * Any metallic foreign body in the eye or brain Other criteria (all participants) * Significant history of neurological or psychiatric disorders * Ongoing medication that may affect cognitive performances * Sensory deficit that may interfere with the experimental design (e.g. uncorrected visual impairment) * Lack of sufficient cooperation during the cognitive tasks * Persons under major legal protection and/or deprived of liberty Other criteria (control participants) \- Global cognitive impairment attested by Mattis Dementia Rating Scale or Mini-Mental State Examination, according to available normative data Other criteria (AD-MCI participants) * 7 items modified Hachinski ischemic score \> 2 (Hachinski et al., 2012) * Dementia (McKahn, et al., 2011)