Ticagrelor Monotherapy After 3 Months in the Patients Treated With New Generation Sirolimus Stent for Acute Coronary Syndrome (TICO Study)

Inclusion Criteria: * Patients ≥ 19 years old * Patients who received new generation sirolimus-eluting (Osiro®) stent implantation for treating ACS * Patients without significant clinical events such as MI, stent thrombosis or revascularization until 3 months after PCI * Provision of informed consent Exclusion Criteria: * Age \> 80 years * Increased risk of bleeding, anemia, thrombocytopenia * A need for oral anticoagulation therapy * Pregnant women or women with potential childbearing * Life expectancy \< 1 year * Patients who treated with strong CYP3A4 inhibitors (e.g. ketoconazole, clarithromycin, nefazodone, ritonavir, or atazanavir) * Patients who had history of intracranial hemorrhage * Moderate to severe hepatic dysfunction * Increased risk of bradycardia-related symptom (Guidance and reference)