The Association Between Adenomyosis/Uterine Myoma and Lower Urinary Tract Symptoms

Far Eastern Memorial Hospital150 enrolled

Overview

The aim of this study is to assess the relationship between adenomyosis/myoma and lower urinary tract symptoms, sexual function and gastrointestinal symptoms.

All outpatient patients were found to have \>3 cm uterine myoma or adenomyosis were invited to participate in this study. The size and location of uterine myoma or adenomyosis and the uterus should be assessed by ultrasonography. Besides, all enrolled female patients will be asked to complete overactive bladder symptom score, female bladder function (UDI-6 \& IIQ-7), female sexual function index, and bowel incontinence assessment questionnaires. In addition, patients who underwent surgeries for myoma or adenomyosis will be requested to complete the above questionnaires at 3 months after surgery. Women with intact uterus should be assessed again by ultrasonography. At least 30 women with age and body mass index matched and without uterine myoma or adenomyosis will be invited to participate in this study as the control group.

Study Type

OBSERVATIONAL

Enrollment

150

Conditions

Adenomyosis Uterine Leiomyoma

Interventions

myomectomy or adenomyomectomyPROCEDURE

Eligibility

Sex: FEMALEMin age: 20 YearsHealthy volunteers:

Medical Language ↔ Plain English

\<Women with myoma or adenomyosis\> Inclusion Criteria: 1. \>20 years old. 2. Myoma: women with \>3 cm uterine myoma 3. Adenomyosis: women with uterus having several dark area (lacunar areas) in one uterine wall or thickening uterine wall \<The control group\> Inclusion criteria: 1. \>20 years old. 2. Women without myoma or adenomyosis \<Both groups\> Exclusion Criteria: 1. The patient has a lower urinary tract infection or acute intestinal inflammation. 2. Previous surgery for the bladder or urethra. 3. History of urinary tract stones or tumors.

Locations (1)

Far-Eastern Memorial Hospital

Banqiao District, New Taipei, Taiwan

RECRUITING

Outcomes

Primary Outcomes

The corrleation coefficient between the size of myoma and Overactive Bladder Symptoms Scores

The Spearman's correlation between the size of uterine myoma and the score of Overactive Bladder Symptoms Scores

Time frame: 12 weeks

Secondary Outcomes

The corrleation coefficient between the size of myoma and the presence of constipation/diarrhea

The Spearman's correlation between the size of uterine myoma and the presence of constipation/diarrhea

Time frame: 12 weeks

Comparison of Overactive Bladder Symptoms Scores between the adenomyosis group and the control group

Comparison of Overactive Bladder Symptoms Scores between the adenomyosis group and the control group by Wilcoxon rank-sum test

Time frame: 12 weeks

Comparisons of the constipation/diarrhea rates between the adenomyosis group and the control group

Comparisons of the constipation/diarrhea rates between the adenomyosis group and the control group by Chi-square test or Fisher's exact test

Time frame: 12 weeks

Central Contacts

Sheng-Mou Hsiao, MD

CONTACT

+89667000 smhsiao2@gmail.com

Data from ClinicalTrials.gov

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