The purpose of this study to determine the association between postoperative pain after cesarean section and several single nucleotide polymorphisms in SCN9A sodium channels gene.
SCN9A gene encodes an alpha subunit of the voltage-gated sodium channel (Nav1.7) and polymorphisms of this gene are associated with severe pain disorders. The impact of the polymorphisms in SCN9A on postoperative pain and opioid consumption after cesarean section is unclear.
Study Type
OBSERVATIONAL
Enrollment
200
Women in 36 to 40 weeks of pregnancy undergoing cesarean section by Pfannenstiel technique
Tramadol will be administered via patient controlled analgesia (PCA) pump in the postoperative period
Gaziosmanpasa University Medical School Hospital
Tokat Province, Turkey (Türkiye)
Pain
The pain will be evaluated with the visual analog scale
Time frame: up to postoperative 24 hours
Opioid consumption
The total amount of the tramadol administered to the patient will be recorded
Time frame: Up to postoperative 24 hours
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