Exertional Rhabdomyolysis- Characterization of Prediction Tests for Return to Duty

Sheba Medical Center50 enrolled

Overview

In order to determine norm values for skeleton muscle disassembly due to physical exertion in healthy and trained population, and developing a prediction test for approval for rhabdomyolysis injuries to return to duty, 50 healthy subjects will undergo a series of different physical tests.

50 healthy civilians volunteers will be recruited for this study. Each subject will undergo the physical tests: anthropometric measurements, wingate test, VO2max test, step test and running on the anaerobic threshold, on separate days. Blood sample, lactic acid level (measured in blood drop - finger sting) and urine sample will be taken before and after every test.

Study Type

INTERVENTIONAL

Allocation

Purpose

BASIC_SCIENCE

Masking

NONE

Enrollment

Conditions

Rhabdomyolysis

Interventions

physical testsOTHER

each subject will undergo the following physical tests: day 1 - anthropometric measurements, wingate test and after 1 hour rest VO2max test. lactic acid levels will be measured before and after both tests. day 2 - step test day 3 - running on the anaerobic threshold. blood sample, lactic acid level (measured in blood drop - finger sting) and urine sample will be taken before and after every test in days 2 and 3.

Eligibility

Sex: MALEMin age: 18 YearsMax age: 30 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * healthy civilians ages 18-30. * above average aerobic and anaerobic fitness. * Without heart, cardiovascular, metabolic or respiratory illnesses. * Without known medical illness or medication use that might endanger the participants. Exclusion Criteria: * existence of any of undesired conditions detailed in the inclusion criteria. * the physician decision.

Locations (1)

Sheba medical center

Tel Litwinsky, Ramat- Gan, Israel

Outcomes

Primary Outcomes

creatine phosphokinase (CPK)

CPK is a marker for muscle damage assessed in blood test. blood sample will be taken before and after step test and running on the anaerobic threshold test.