Monosialoganglioside Preventing Neurotoxicity Induced by Albumin-bound Paclitaxel Chemotherapy in Lung Cancer Patients

Inclusion Criteria: * Cytological and histological confirmation of unresectable locally advanced or metastatic lung cancer diagnosis * No peripheral nervous system diseases exists before * Within 4 weeks before treatment, did not receive other adverse reaction of drugs may cause similar neurotoxicity * Enough organ functions reservation and appropriate performance status for chemotherapy * Expected survival period is more than 3 months Exclusion Criteria: * Known or assignment of any of these products to test drugs allergic agent composition * With peripheral neuropathy by any cause before treatment * With other neurological dysfunction which can cause inaccurate record of the occurrence of neurotoxicity and severity * Patients with poor general condition to receive chemotherapy * Genetic glucolipid metabolic abnormalities * Patients (male or female) have fertility possibility but not willing to or not to adopt effective contraception * Patients cann't avoid neurotrophic drugs * According to the researcher's judgment, the situations inappropriate for patients with ganglioside medication