General anesthesia lowers FRC thereby promoting airway closure and absorption atelectasis. Alveolar recruitment manoeuvers recruit collapsed alveoli, increase gas exchange, and improve arterial oxygenation.
General anesthesia lowers FRC thereby promoting airway closure and absorption atelectasis. Alveolar recruitment manoeuvers recruit collapsed alveoli, increase gas exchange, and improve arterial oxygenation. However, the effect of recruitment manoeuvre is short lasting and does not extend to the post operative period. Postoperative CPAP keeps the lung open and can improve oxygenation in the early postoperative period.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
60
patients will be mechanically ventilated and a vital capacity manoeuvre for lung inflation will be done by increasing the PIP to 35 cmH2o for 15 seconds followed by PEEP until extubation.
patients will be mechanically ventilated and a vital capacity manoeuvre for lung inflation will be done by increasing the PIP to 35 cmH2o for 15 seconds followed by PEEP until extubation and a CPAP mask will be applied immediately postoperative.
Pediatric hospital
Asyut, Assiut Governorate, Egypt
(A-a) DO2
arterial blood gas will be withdrawn 1 hour after extubation and the alveolar minus arterial oxygen difference will be calculated for assessment of oxygenation
Time frame: 1 hour after extubation
PaO2
arterial blood gas samples will be withdrawn to assess Pa O2.
Time frame: intra-operative and 1hour postoperative
PaCO2
arterial blood gas samples will be withdrawn to assess PaCO2.
Time frame: intra-operative and 1hour postoperative
PH
arterial blood gas samples will be withdrawn to assess PH.
Time frame: intra-operative and 1hour postoperative
Respiratory mechanics
intra-operative ventilator data will be recorded to measure respiratory mechanics such as dynamic and statistic compliance
Time frame: Intraoperative
non invasive mean arterial pressure
non invasive mean arterial pressure will be recorded before and after recruitment manouvre, after pneumoperitonium and after pneumoperitonium deflation
Time frame: intraoperative and 1hour postoperative
Heart rate
the heart rate will be recorded before and after recruitment manoeuvre, after pneumoperitonium, and after pneumoperitonium deflation and early postoperative..
Time frame: intraoperative and 1hour postoperative
Peripheral arterial oxygenation SPO2%
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
The SPO2% will be recorded before and after recruitment manouvre, after peumoperitoneum inflation and after pneumoperitoneum deflation and early postoperative
Time frame: intraoperative and 1hour postoperative