The primary aim of the study is to compare the effect of three different interventions on lifestyle risk factors and biological risk factors for type 2 diabetes in depressed Cambodians. The three different interventions are lifestyle, lifestyle plus medication therapy management, and social services.
Cambodian Americans have high risk for major depressive disorder and for type 2 diabetes. Depression is a known risk factor for diabetes. Some antidepressants can also increase risk of diabetes by causing weight gain. DREAM will test the effect of lifestyle and medication therapy management (MTM) compared to social services (control) on diabetes risk among depressed Cambodian Americans. Community health workers (CHWs) will deliver the lifestyle intervention and assist pharmacists with MTM. Lifestyle and biological risk factors for diabetes, such as depressive symptoms, HbA1c and insulin sensitivity, will be measured before and after the interventions.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
182
Uconn Health
Farmington, Connecticut, United States
Khmer Health Advocates
West Hartford, Connecticut, United States
Center for Southeast Asians
Providence, Rhode Island, United States
Lifestyle risk for type 2 diabetes
Change from baseline in depressive symptoms according to the Hopkins Symptom Checklist
Time frame: 12 months and 15 months
Biological risk for type 2 diabetes
Change from baseline in HbA1c and insulin resistance according to logHOMA-IR
Time frame: 12 months and 15 months
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