A Study of [14c]-Samidorphan (Also Known as ALKS 33) in Healthy, Male Volunteers

Inclusion Criteria: * Body mass index (BMI) of greater than/equal to 19 and less than/equal to 32 kg/m\^2 at screening (minimum weight of 50.0 kg) * Generally good health * Subjects must agree to reduce the risk of a female partner becoming pregnant during the study and for 30 days after the last dose of the study drug by abstinence from heterosexual relationships or use of a reliable contraceptive method * Additional criteria may apply Exclusion Criteria: * Clinically significant illness within 30 days * History of alcohol or opioid dependence, or positive urine toxicological screen for marijuana, cocaine, amphetamines, opioids, barbiturates, and benzodiazepines * History of oral or gastrointestinal disease * Irregular bowel or bladder function * History of allergy or hypersensitivity to opioid medications or opioid antagonists (eg, naltrexone, naloxone) * Current or pending legal charges or probation that would interfere with study conduct * Use of alcohol within 24 hours prior to admission or urine positive test for alcohol at screening or admission * Tobacco or nicotine use within 90 days * Anticipated need for prescription medicines during the study period * Additional criteria may apply