This protocol aims at assessing the efficacy of performing catheter ablation for atrial fibrillation (AF) with laser catheters versus performing it with radiofrequency (RF) catheters. In order to study laser catheter ablation efficacy, MRI analysis of the lesions 3 months after the procedure will be performed in both groups. MRI analysis will detect ablation gaps in the lesions encircling pulmonary veins. The primary endpoint will compare the number of gaps in the laser catheter and the RF group. The secondary endpoint of the study is recurrence of AF after 12 months. The target population of the study is patients with paroxysmal or persistent AF undergoing AF ablation.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
64
Pulmonary vein isolation using the laser ablation catheter
Pulmonary vein isolation using the RF ablation catheter
Hospital Clínic de Barcelona
Barcelona, Catalonia, Spain
Presence of large gaps in the delayed enhancement MRI (DE-MRI)
The presence of MRI ablation gaps around the pulmonary veins evaluated with MRI images of the patient acquired three months after the ablation procedure. A large gap is described as a GAP that is larger or equal than 20% of the vein perimeter.
Time frame: 3 months
To determine the number of patients that present atrial fibrillation after the ablation procedure
The number of patients that present a recurrence in their atrial fibrillation after the ablation procedure during the first year.
Time frame: 1 year
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