Physiological and Clinical Changes in NHF Therapy

University of Leipzig64 enrolled

Overview

The study explores the changes in pressure, volume and in hypercapnia in patients with COPD and ILD. The investigators will use different application forms.

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Chronic Obstructive Pulmonary Disease Hypercapnia Interstitital Lung Disease

Interventions

Nasal Highflow (NHF)DEVICE

changes in breathing physiology in NHF

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * COPD, ILD Exclusion Criteria: * Unstable disease

Locations (1)

Jens Bräunlich

Leipzig, Saxony, Germany

Outcomes

Primary Outcomes

changes in mean airway pressure (mbar)

Time frame: 1 month

changes in tidal and minute volume (l)

Time frame: 1 month

changes in breathing frequency (beats/ minute)

Time frame: 1 month

Secondary Outcomes

changes in partial pressure of carbon dioxide (CO2) in arterial blood (pCO2)

Time frame: 4 month

Data from ClinicalTrials.gov

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