Nasopharyngeal carcinoma (NPC) is usually treated with chemoradiotherapy. While the effects of this treatment on cochlear function is well characterized, its effect on vestibular function is not well studied. In this study the investigators will study the vestibular function of 50 patients undergoing chemoradiotherapy for NPC both before and after treatment in order to better define its effects. All patients will undergo a validated questionnaire (dizziness handicap index), posturography, audiometry and vestibular-evoked myogenic potentials.
Study Type
OBSERVATIONAL
Enrollment
50
Note that this is standard care for NPC and patients are not assigned to different intervention groups. All patients in the study will receive the same treatment (chemoradiotherapy) and will be observed for changes in vestibular function.
Department of Otolaryngology, Rabin Medical Center
Petah Tikva, Israel
Subjective dizziness and vestibular dysfunction using the dizziness handicap index
Time frame: 6 months after completion of treatment
Hearing level using standard audiometry
Time frame: 6 months after completion of treatment
Objective vestibular function using posturography
Time frame: 6 months after completion of treatment
Vestibular saccular function using vestibular-evoked myogenic potentials
Time frame: 6 months after completion of treatment
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