Effect of Gum Chewing on Bowel Cleansing Before Colonoscopy

Changhai Hospital300 enrolled

Overview

In this randomized controlled study, consecutive outpatients scheduled for elective colonoscopy were randomized into two groups. Group A patients (n = 150) used 2 L PEG before colonoscopy. Patients in group B (n = 150) were additionally advised to chew sugarless gum plus 2 L PEG, The overall quality of colonoscopy cleaning was evaluated using the Boston Bowel Preparation Scale by endoscopists who was blinded to the intervention. Difficulty of procedure, patients' tolerance, and adverse events were also evaluated.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

SCREENING

Masking

SINGLE

Enrollment

300

Conditions

Bowel Preparation Scale Adenoma Detection Rate

Interventions

gum+PEGDIETARY_SUPPLEMENT

chew sugarless gum

polyethylene glycolDRUG

2L PEG

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * All adults (18-65) who were referred for outpatient colonoscopy. Exclusion Criteria: * under 18 years or More than 65 years * previous abdominal surgery * major psychiatric disorders * pregnancy * presence of any contraindications for colonoscopy(eg, severe heart failure) * recent inadequate colonoscopy history

Outcomes

Primary Outcomes

Boston Bowel Preparation Scale

Time frame: 2 days

Secondary Outcomes

number of patient tolerability

Time frame: 2 days

number of patient willingness to repeat preparation

Time frame: 2 days

Adenoma Detection Rate

Time frame: 2 days

Data from ClinicalTrials.gov

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