Normobaric Hypoxic Training and Multiple Sclerosis

Charite University, Berlin, Germany39 enrolled

Overview

To study the effects of normobaric hypoxic training on cardiorespiratory fitness, resting, postprandial and exercise activity energy expenditure, immunoregulatory functions and serum erythropoietin levels in relapsing-remitting multiple sclerosis patients.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

SINGLE

Enrollment

Conditions

Multiple Sclerosis

Interventions

Hypoxic trainingOTHER

Hypoxic training 3 times per week four four weeks

Normoxic trainingOTHER

Normoxic training 3 times per week four four weeks

Eligibility

Sex: ALLMin age: 20 YearsMax age: 60 Years

Medical Language ↔ Plain English

Inclusion Criteria: * stable immunomodulatory therapy * expanded disability status scale score \< 4.5 * body mass index 18.5 - 29.9 kg/m2 Exclusion Criteria: * clinically relevant heart, lung, liver, and kidney diseases

Locations (1)

Experimental & Clinical Research Center

Berlin, Germany

Outcomes

Primary Outcomes

Activity energy expenditure measured by indirect calorimetry (respiratory chamber)

Time frame: Change from baseline at 4 weeks

Data from ClinicalTrials.gov

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