Background: To compare the effectiveness of open flap debridement (OFD) alone and OFD along with either Autologous Platelet Rich Fibrin (PRF) or Titanium Platelet Rich Fibrin (TPRF) in the treatment of intrabony defects (IBDs). Materials and methods: Study was conducted on subjects reporting to the Department of Periodontics, The Oxford Dental College and Hospital, Bangalore. 38 subjects with 90 periodontal IBDs of moderate to severe periodontitis were selected and assigned to OFD alone (group I) or OFD with Autologous PRF (group II) or OFD with TPRF (group III). In each subject, a minimum number of two sextants were present with probing pocket depths (PPD) ≥5mm in at least three teeth.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
38
Oral prophylaxis followed by Open flap debridement (OFD)
Oral prophylaxis followed by Open flap debridement (OFD) with Platelet rich fibrin (PRF) placement into the bone defect
Oral prophylaxis followed by Open flap debridement (OFD) with Titanium Platelet rich fibrin (TPRF) placement into the bone defect
Government Dental College and Research Institute
Bangalore, Karnataka, India
The Oxford Dental College
Bangalore, Karnataka, India
defect depth reduction (DDR)
Time frame: Change from baseline to 9 months
change in clinical attachment level (CAL)
Time frame: Change from baseline to 9 months
change in probing pocket depths (PPD)
Time frame: Change from baseline to 9 months
change in plaque index (PI)
Time frame: Change from baseline to 9 months
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