The primary purpose of this study is to assess the tolerability of prexasertib in Japanese participants with advanced solid cancers.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
12
Administered IV
For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
Chiba, Japan
For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
Tokyo, Japan
Number of Participants with Prexasertib Dose-Limiting Toxicities (DLT)
Time frame: Cycle 1 (14 day cycle)
Pharmacokinetics (PK): Maximum Concentration (Cmax) of Prexasertib
Time frame: Pre-dose up to 7 Days Post Treatment in Cycle 1/2 (Approximately 7 Days)
Pharmacokinetics (PK): Area Under Curve (AUC) of Prexasertib
Time frame: Pre-dose up to 7 Days Post Treatment in Cycle1/2 (Approximately 7 Days)
Percentage of Participants with a Tumor Response
Time frame: Baseline to Study Completion (Approximately 24 weeks)
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.