3D Ballistocardiography in Microgravity

University Hospital, Caen18 enrolled

Overview

3-D Ballistocardiography (BCG) recording was performed in microgravity during the Spacelab D2 missions on a single astronaut. The results from this experiment have been published in the literature: the influence of respiration have been demonstrated and the signal processing methodology for the reconstruction of the displacement in one cardiac cycle have been developed. A 3D-BCG sensor has been developed and a collaboration to perform a sustained microgravity experiment onboard the Russian segment of ISS has been initiated. To be integrated in the PNEUMOCARD device, this new sensor needs to be tested in microgravity before implemented on ISS. The aim of the present parabolic flight study is to serve as a feasibility demonstrator and test bed in order to evaluate the feasibility of 3D-BCG in sustained microgravity and to test whether the sensitivity of the developed 3D-BCG sensor is appropriate

Study Type

INTERVENTIONAL

Allocation

Purpose

BASIC_SCIENCE

Masking

NONE

Enrollment

Conditions

Healthy

Interventions

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Healthy volunteers (men or women) * Aged from 18 to 65 * Affiliated to a Social Security system and, for non-French resident, holding a European Health Insurance Card (EHIC) * Who accepted to take part in the study * Who have given their written stated consent * Whose 4 chamber view of the heart during a breath hold is easy to get during a routine cardiac echocardiography (M-Mode - apical view). * Who has passed a medical examination similar to a standard aviation medical examination for private pilot aptitude (JAR FCL3 Class 2 medical examination). There will be no additional test performed for subject selection. Exclusion Criteria: * Person who took part in a previous biomedical research protocol, of which exclusion period is not terminated * Difficulty to obtain a clear echocardiography. * Pregnant women

Outcomes

Primary Outcomes

Heart rate

evaluated by BCG, ECG, ICG and echocardiography during the free-floating protocol

Time frame: baseline

stroke volume

evaluated by BCG, ECG, ICG and echocardiography during the free-floating protocol

Time frame: baseline

ejection fraction

evaluated by BCG, ECG, ICG and echocardiography during the free-floating protocol

Time frame: baseline

3D Ballistocardiography in Microgravity

Overview

Conditions

Interventions

Eligibility

Locations (1)

Outcomes

Primary Outcomes