Effects of Prebiotic Oral Healthcare Products as an Adjunct to Non-surgical Periodontal Therapy

Inclusion Criteria: * 40 patients * ≥ 36 years of age \- Page 4 of 4 \[DRAFT\] - * No previous scaling and rootplaning * Clinical diagnosis: severe generalized periodontitis characterized by the presence of \> 14 affected teeth when \> 14 teeth are present (if number of teeth present is \< 14, 8-14 teeth need to be affected) with an attachment loss of \> 6mm prior to initial non-surgical periodontal therapy. * A minimum of 3 natural teeth in every quadrant * Willing and able to give written informed consent Exclusion Criteria: * Patients with aggressive periodontitis or necrotizing periodontitis * Patients who smoke * Pregnant or lactating woman * A history of diabetes, rheumatic fever, liver or kidney disease, neurological deficiencies, or use of medication which may affect periodontal tissue, (phenytoin, cyclosporin, nifedipine, chronic use of non-steroidal antiinflammatory drugs) * Patients with poorly controlled diabetes * Patients taking bisphosphonate mediation * Patient who have taken systemic antibiotics 3 months prior to treatment