The Use of a Probiotic Lozenge in the Treatment of Peri-implantitis

N/ACompletedNCT02520401

Universitaire Ziekenhuizen KU Leuven22 enrolled

Overview

This studies aims to investigate the effect of a probiotics in peri-implantitis patients as an adjunct to non-surgical therapy.

This studies aims to investigate the effect of a probiotics in peri-implantitis patients as an adjunct to non-surgical therapy. Study design: This study will be a single centre (Department of Oral Health Sciences, University Hospitals Leuven), double blind randomized, placebo controlled clinical trial. The randomization (by means of a computer program) and double blind design are thought to minimize the bias of the investigator and patients. Selection of the study population: Adults, who consult at the departement of Periodontology at the University Hospital Leuven, with peri-implantitis and who fit the inclusion criteria will be asked to participate in this study.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

QUADRUPLE

Enrollment

Conditions

Peri-implantitis

Interventions

Probiotic - BioGaiaOTHER

Use of a probiotic tablet

PlaceboOTHER

Use of a placebo tablet

Eligibility

Sex: ALLMin age: 18 YearsMax age: 99 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * \>18 years of age * Patients with at least one implant\* diagnosed with initial peri-implantitis. * Willing and able to give written informed consent * No signs of acute periodontitis * presence of keratinized tissue around treated implant(s) Exclusion Criteria: * patients who smoke * patients with periodontitis * pregnant or lactating woman * patients with poorly controlled diabetes * patients taking bisphosphonate mediation * patient who had taken systemic antibiotics 3 months prior to treatment * peri-implantitis treatment 12 months prior intake

Locations (1)

UZLeuven

Leuven, Belgium