Study of the Wear of a Highly Cross-linked Polyethylene Acetabular Doped With Vitamin E and Coated With Titanium in Total Hip Replacement

University Hospital, Caen62 enrolled

Overview

The total hip replacement, with over 120,000 cases per year in France, provides short term, excellent functional results and a significant improvement in quality of life, in almost all cases. However, the observation has shown that the lifetime of the implants is limited due to aseptic loosening. One of the factors associated with these failures is a peri-prosthetic osteolysis wherein the polyethylene wear debris (PE) have been implicated. Several solutions have been proposed: change the friction torque (hard-hard pairs using ceramic or metal on the two components of the couple) or improving quality polyethylene. Improving the resistance of polyethylene wear is the primary objective evaluated in this study.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

Conditions

Total Hip Replacement

Interventions

Eligibility

Sex: ALLMin age: 18 YearsMax age: 75 Years

Medical Language ↔ Plain English

Inclusion Criteria: * patients aged men and women 18 to 75 years * with a primary or secondary osteoarthritis or osteonecrosis * having a functional disorder requiring the installation of a total hip prosthesis of primary Exclusion Criteria: * patients aged 76 years or more * pregnant or desiring to be for the duration of the study * minors or adults protected * repeated hip replacement * cephalic prosthesis recovery or intermediate * repeated cupules * primary or secondary malignant tumor of the hip

Study of the Wear of a Highly Cross-linked Polyethylene Acetabular Doped With Vitamin E and Coated With Titanium in Total Hip Replacement

Overview

Conditions

Interventions

Eligibility

Locations (1)

Outcomes

Primary Outcomes