Post Market Non-Inferiority Study Comparing Triojection® to Discectomy for Lumbar Disc Herniation

Inclusion Criteria 1. Patient is willing to provide informed consent. 2. Clinical and radiographic evidence of one, and only one, symptomatic protruding or extruded disc between L1 and S1. 3. The herniated disc should have a disc height of at least 50% that of the normal adjacent disc levels, as determined by the investigator. 4. The signal intensity of the herniated disc material should be equal or greater than the nucleus pulposus of the herniated disc. 5. The patient must have pain in a dermatomal distribution consistent with their radiographic findings 6. Leg pain greater than or equal to 5 on the NRS scale 7. Symptoms for at least 6 weeks 8. Willingness to complete all follow-up evaluations 9. Patient aged 18-65 years 10. BMI\<40 Exclusion Criteria: 1. Patients with a disc herniation extending past the facet joint 2. Presence of a non-contiguous disc fragment 3. Impairment of bladder/bowel function or motor impairment in the affected leg 4. An epidural steroid injection in the past 2 weeks 5. Previous discectomy, arthroplasty or fusion at any lumbar level 6. In patients with L5-S1 disc herniation, a congenital condition where the L5 vertebral body is either fused to the sacrum or the L5-S1 disc is not fully formed as a normal adult disc. 7. Symptomatic lumbar stenosis or listhesis 8. Symptomatic sacroiliac joint 9. Symptomatic foraminal stenosis due to severe degenerative disc disease 10. History of spinal tumor, fracture or infection 11. Females of childbearing age that are known to be pregnant or wishing to become pregnant during the study 12. Fibromyalgia 13. Active infection 14. Metastatic cancer within the past 5 years 15. Pending litigation against a health care provider 16. More than 3 months of continuous sick leave prior to enrollment. 17. Known drug or alcohol abuse 18. Diagnosed psychiatric disease or psychological distress caused by recent trauma like divorce, death of a member family or loss of a job 19. Patient known to be affected by favism (G6PD deficiency)