The aim of this study is to evaluate the safety and effectivity of Ginkgo diterpene lactone meglumine injection tn the treatment of acute ischemic stroke
After randomized to 90 + 7 days mRS 0-1 points is the Primary Outcome Measure,evaluate the safety and effectivity of Ginkgo diterpene lactone meglumine injection tn the treatment of acute ischemic stroke
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
3,452
5 ml/times, 1 time/day.Before use, the drug slowly added to the 0.9% sodium chloride injection diluted in 250 ml, slow intravenous drip.
5 ml/times, 1 time/day.Before use, the drug slowly added to the 0.9% sodium chloride injection diluted in 250 ml, slow intravenous drip.
Tiantan Hospital
Beijing, Beijing Municipality, China
Proportion of patients with Modified Rankin Scale (mRS) less than or equal to 1 .
Time frame: 90 days
Proportion of patients with National Institutes of Health Stroke Score (NIHSS) rising 4 or more points, three points, two points, one of the subjects changes from baseline to randomized 7 days.
Time frame: Baseline, 7days
Proportion of patients with National Institutes of Health Stroke Score (NIHSS) reducing 4 points or more changes from baseline to randomized 7 days,14 days.
Time frame: Baseline,7 days,14 days,
Proportion of patients with Modified Rankin Scale (mRS) reaching 0-2 .
Time frame: 90 days
The Montreal Cognitive Assessment (MoCA) scale changes from baseline to randomized 14 days,90 days.
Time frame: Baseline,14 days,90 days
The EuroQol-5 Dimensions (EQ-5D) scale changes from baseline to randomized 14 days,90 days.
Time frame: Baseline,14 days,90 days
The all-cause mortality
Time frame: 90 days
Ischemic stroke recurrence rate
Time frame: 90 days
Composite incidence of vascular events
Time frame: 90 days
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.