Adipose Derived Stem Cells in Facial Fat Grafting

Inclusion Criteria: 1. Female or Male, Age 18 to 70 years old 2. Subjects that are eligible for liposuction and facial fat grafting procedures for cosmetic purposes and facial atrophy. 3. Subjects must require augmentation to the infra-malar region. Furthermore, facial engraftment to additional, non-study related regions is optional, but not required. 4. Inframalar Atrophy Assessment Scale of 2 to 4 5. Facial volume defect range: 2 to 10 mL 6. Body Mass Index (BMI) between and including 22 and 29 7. Able to understand and provide written and verbal informed consent 8. Fitzpatrick Scale 1 to 6 Exclusion Criteria: 1. Currently taking or have taken None Steroid Anti-inflammatory Drugs (NSAIDs) within last two weeks or corticosteroids within the last six weeks prior to screening 2. Diagnosis of any of the following medical conditions: * Active malignancy (diagnosed within 5 years), except for treated non-melanoma skin cancer or other non-invasive or in-situ neoplasm (e.g. cervical cancer) * Active infection * Type I or Type II Diabetes * Skin/Bone deformities in the face, including scaring or hyperpigmentation within the graft site. 3. Subjects who are unlikely to comply with the protocol (e.g., uncooperative attitude, inability to return for subsequent visits, dementia, and/or otherwise considered by the Investigator to be unlikely to complete the study) 4. Subjects with a known drug or alcohol dependence within the past 12 months as judged by the Investigator 5. Dermal fillers or facial reconstruction within the past 24 months, Subjects must also refrain from such procedures during the duration of the study. 6. Subjects with major illnesses involving the renal, hepatic, cardiovascular, and/or nervous systems. 7. Subjects with elevated kidney and/or liver functions 8. Any other disease condition or laboratory results that in the opinion of the investigator may be clinically significant and render the subject inappropriate for the study procedure(s), may alter the accuracy of study results, or increase risk for subjects. 9. Subjects with life-expectancies less than 9 months 10. Subjects with known collagenase allergies 11. Subjects with idiopathic or drug-induced coagulopathy 12. Pregnant females 13. On radiotherapy or chemotherapy agents 14. Taking strong CYP450 inhibitors 15. Subjects with a history of keloids or hypertrophic scar formations 16. Previous treatment with any synthetic fillers in the inframalar area