The Effect of Meal Composition on Blood Lipids

Texas Christian University24 enrolled

Overview

The purpose of this study is to see if a high-protein meal leads to a better postprandial (after a meal) blood lipid profile compared to a high-monounsaturated meal.

The effect of a high-protein diet compared to a high-monounsaturated fat diet on fasting lipids is controversial (1,2), In addition, these studies did not examine the effect of a high-protein compared to a high-monounsaturated meal on postprandial lipid concentrations. Postprandial lipid responses are important to examine since they are associated with heart disease (3,4). In addition, most individuals in Western countries are in a postprandial state for majority of the day. The present study will compare the effect of a high-protein meal versus a high-monounsaturated fat meal on postprandial lipid responses.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Dyslipidemia

Interventions

High-Protein ConditionOTHER

The participants will be fed a high-protein meal

High-Monounsaturated Fat ConditionOTHER

The participants will be fed a high-monounsaturated fat meal

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Men and women ages 18-65 years. Exclusion Criteria: * Use of medications or supplements that affect lipid levels, body weight, or blood glucose, * following a weight loss diet, * being a vegan, * smoking, * heavy alcohol use, * pregnancy, * lactation, * severe depression, * eating disorders, * presence of liver, kidney, gastrointestinal, adrenal, or untreated thyroid disease, * diabetes, * lactose intolerance, * documented mal-absorption, or * bowel surgery that affects absorption.

Locations (1)

Texas Christian University

Fort Worth, Texas, United States