Diabetes mellitus is the most common endocrine disorder, causes many complications such as micro- and macro-vascular diseases. Various kinds of antidiabetic drugs have been developed, but most of them have side effects. Recently, the use of natural plant products has gained more attention among scientists in order to prevent diabetic vascular complications. Curcumin is a natural yellow product derived from the turmeric rhizome which has shown to be non-toxic and exhibits various bio¬logical activities such as anti-oxidant, anti-inflammatory, anti-carcinogenic, and anti-diabetic effects. Curcumin is effective in reducing glycemic index and hyperlipidemia in rodent models and is relatively inexpensive and safe. Most of the studies conducted on animal model, and just a few of them are on human model. The present study was planned to evaluate the effects of curcumin supplementation The effect of curcumin supplementation on anthropometric indices, insulin resistance and oxidative stress in patients with type 2 diabetes
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
44
NNFTRI clinic
Tehran, Iran
fasting blood sugar
Time frame: 10 weeks
Insulin
Time frame: 10 week
HbA1c
Time frame: 10 week
Homeostatic Model Assessment of Insulin Resistance
Time frame: 10 week
Change in pancreatic B-cell function
Time frame: 10 week
total capacity antioxidant
Time frame: 10 weeks
Malondialdehyde
Time frame: 10 week
Body mass index
Time frame: 10 week
Waist circumference
Time frame: 10 week
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