Study of Chemotherapy-Induced Hair Changes and Alopecia, Skin Aging and Nail Changes in Women With Non-Metastatic Breast Cancer

Inclusion Criteria: * Women newly diagnosed with non-metastatic breast cancer (stage 0-III, any receptor type) at the time of starting chemotherapy (dd-AC-T, CMF, Newer Combination Regimens) or endocrine therapy (tamoxifen, anastrozole, letrozole, exemestane) * Women ≥ 18 years at the time of enrollment into the study * Able to communicate in English and participate in the informed consent process * Able to comply with the follow-up visits, assessments, answering questionnaires Exclusion Criteria: * Metastatic breast cancer * Follow-up care/visits not scheduled at MSKCC * Any current alopecia especially due to an active scalp and/or hair disorder (e.g. alopecia areata), or a pre-existing condition with sequelae (e.g. scarring alopecia) * Currently active or uncontrolled medical condition \[e.g. thyroid disorder, auto-immune connective tissue disease (e.g. SLE), BMT complications (GVHD)\] or medication intake (e.g. HRT), affecting scalp hair * Prior systemic treatment for any malignancy * Active secondary cancer requiring cytotoxic chemotherapy * Planned (or a history of) radiation therapy to the head * Vulnerable populations \[e.g. decisionally impaired (cognitive, psychiatric), terminally ill, prisoners\], or patients who, in the opinion of the investigator have a condition that precludes their ability to provide an informed consent * Men Volunteer Inclusion Criteria: * Post menopausal women, with menopausal status defined as (per self report): * Bilateral salpingo-oophorectomy independent of age * If natural menopause, age ≥ 50 with cessation of menses for at least 12 months * Or premenopausal women with premenopausal status defined as \<53 years of age with no cessation of menses * Able to communicate in English and participate in the informed consent process * Able to comply with the baseline assessments and answering questionnaires * Women \>/= 18 years at the time of enrollment into the study