Relationship Between a Combined Index of Diastolic and Systolic Performance and Intraoperative Hemodynamic Changes During Off-pump Coronary Bypass Surgery

Yonsei University120 enrolled

Overview

As considering the close relationship between systolic dysfunction and diastolic dysfunction, the EAS index e'/(a' x s') including systolic and diastolic function could be expected to predict hemodynamic changes during off-pump coronary artery bypass surgery(OPCAB). Exposure of the grafting site during OPCAB needs displacement of the heart, resulting in hemodynamic instability. Therefore the investigators are going to evaluate EAS index with preoperative Transthoracic echocardiography(TTE) and want to know the relationship between preoperative EAS index and intraoperative hemodynamic changes in patients undergoing OPCAB, in a prospective observational study.

Study Type

OBSERVATIONAL

Enrollment

120

Conditions

Coronary Artery Obstructive Disease

Eligibility

Sex: ALLMin age: 20 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Age ≥ 20 2. Patients undergoing multivessel off-pump coronary artery bypass surgery Exclusion Criteria: 1. Age \< 20 2. Patients with valvular heart disease 3. Congestive heart failure, NYHA class ≥III 4. Emergency surgery 5. Patients with arrhythmia 6. ST segment elevation myocardial infarction

Locations (1)

Department of Anaesthesiology and Pain Medicine, Yonsei University College of Medicine

Outcomes

Primary Outcomes

sequential changes of SvO2

Mixed venous oxygen saturation(SvO2) reflects the balance of oxygen supply and demand immediately. Cardiac index(CI) also is a useful marker of how well the heart is functioning. Both variables can show the hemodynamic instability. With the comparison of EAS index and variables including SvO2 and CI, Investigator may draw the predictable value of the EAS index for predicting hemodynamic instability during OPCAB.

Time frame: during OPCAB surgery

sequential changes of CI

Time frame: during OPCAB surgery