The purpose of this clinical trial is to prospectively evaluate RA activity using the assessment of change in DAS28 under local conditions in Slovakia in participants who are treated with subcutaneously administered tocilizumab pursuant to the recommendations of the Ministry of Health of the Slovak Republic in order to better assess the disease activity and impairment of the joint function.
Study Type
OBSERVATIONAL
Enrollment
60
Tocilizumab will be administered at 162 mg SC injection for 48 weeks.
Unnamed facility
Banská Bystrica, Slovakia
Unnamed facility
Bratislava, Slovakia
Unnamed facility
Bratislava, Slovakia
Unnamed facility
Nitra, Slovakia
Unnamed facility
Piešťany, Slovakia
Average change from baseline in DAS28
Time frame: up to Week 24
Average change from baseline in DAS28
Time frame: up to Week 48
Percent of participants achieving clinical remission defined as a DAS28 <2.6
Time frame: Baseline, Week 12, 24, 36, and 48
Percentage of participants achieving a DAS28 >=3.2
Time frame: Baseline, Week 12, 24, 36, and 48
Evaluation of participant's pain using visual analogue scale (VAS)
Time frame: Baseline, Week 12, 24, 36, and 48
Evaluation of the disease activity by participant using VAS
Time frame: Baseline, Week 12, 24, 36, and 48
Evaluation of the disease activity by Doctor using VAS
Time frame: Baseline, Week 12, 24, 36, and 48
DAS28-joint count (erythrocyte sedimentation rate) [DAS28(ESR)] score
Time frame: Baseline, Week 12, 24, 36, and 48
DAS28-joint count (C-reactive protein) [DAS28(CRP)] score
Time frame: Baseline, Week 12, 24, 36, and 48
Absolute and percent change in the Health Assessment Questionnaire (HAQ)
Time frame: Baseline, Week 12, 24, 36, and 48
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