The purpose of this study is to assess whether lower fluorescein sodium dosage can perceive the same detection rate per patient and per lesion for the detection of gastric intestinal metaplasia.
Gastric intestinal metaplasia is regarded as an important premalignant lesion for intestinal type gastric cancer. Currently, the histological assessment of gastric intestinal metaplasia still relies on the biopsies took from five sites that the updated Sydney System recommended. This study aims to compare the diagnostic yield of gastric intestinal metaplasia from two different fluorescein sodium dosage and assess whether lower fluorescein sodium dosage can perceive the same detection rate per patient and per lesion for the detection of gastric intestinal metaplasia.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
DIAGNOSTIC
Masking
DOUBLE
Enrollment
180
fluorescein Sodium Dose of 0.02ml/kg on gastric intestinal metapalsia
fluorescein Sodium Dose of 0.1ml/kg on gastric intestinal metapalsia
Department of Gastroenterology, Qilu Hospital, Shandong University
Jinan, Shandong, China
RECRUITINGDifference of the detection rate of gastric intestinal metaplasia between two fluosecein sodium dosage in a per-pateint analysis
Time frame: six months
Difference of the detection rate of gastric intestinal metaplasia between two dosage fluosecein sodium in a per-biopsy analysis
Time frame: six months
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