Evaluation of Nebulization and Positive Expiratory Pressure Combination

Cliniques universitaires Saint-Luc- Université Catholique de Louvain15 enrolled

Overview

The purpose of this study is to compare the efficiency of nebulization and positive expiratory pressure combination

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Sex: ALLMin age: 16 YearsMax age: 55 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Stable cystic fibrosis patients older than 16 y.o. * Healthy subjects Exclusion Criteria: * Kidney failure * No pregnancy

Cliniques universitaires Saint-Luc

Brussels, Belgium

RECRUITING

Urinary excretion of amikacin

Pharmacokinetic study of the urinary excretion of amikacin after nebulization

Time frame: 24 hours after the nebulization

breathing pattern

recoding of frequency and tidal volume during the nebulization

Time frame: participants will be recorded for the duration of the nebulization, an expected average of 15 minutes

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