This trial is conducted in Europe. The aim of this trial is to compare pharmacodynamic (the effect of the investigated drug on the body) and pharmacokinetic (the exposure of the trial drug in the body) properties of insulin degludec and insulin glargine 300 U/mL at steady-state conditions in subjects with type 1 diabetes mellitus.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
60
Dose levels will be 0.4 U/kg body weight. The trial products will be administered subcutaneously (s.c., under the skin) once daily.
Dose levels will be 0.4 U/kg body weight. The trial products will be administered subcutaneously (s.c., under the skin) once daily.
Novo Nordisk Investigational Site
Neuss, Germany
Area under the glucose infusion rate curve
Time frame: During one dosing interval (0-24h) at steady-state. At day 6, 9 and 12
Area under the glucose infusion rate curve
Time frame: During one dosing interval at steady state.At day 6, 9 and 12
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