Primary goal of this study is the analysis of HLA (Human leucocyte antigen) formation in severly burned patients. Potential HLA triggers in the treatment of severely burned patients are blood products, assist devices or temporary allogeneic skin. Besides that, inflammatory markers, such as WBC (white blood cell count), CRP (C-reactive protein), PCT (Procalcitonin) and two novel biomarkers (PSP (pancreatic stone protein), ST2) are to be investigated in severely burned patients.
Study Type
OBSERVATIONAL
Enrollment
50
University Hospital Zurich
Zurich, Switzerland
RECRUITINGHLA antibody formation (HLA Sensitization) (Unit: PRA in %)
The degree of sensitization is reported as the percentage of CDC (Complement dependent Cytotoxicity) Panel Reactive Antibody (PRA). Unit is %.
Time frame: Change from Baseline (admission) in HLA antibody count at 2 weeks, 4 weeks, 3 months and 6 months
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