Assessment of the Neurovascular Microcirculatory Response in Diabetes Type 1 Patients

University Hospital, Angers40 enrolled

Overview

This study aims to see whether or not the diabetes 1 patients have a neurovascular microcirculatory dysfunction using various microvascular tests which have been previously validated. Microvascular responses will be assessed by Laser Speckle Contrast Imaging and expressed in Laser Speckle Perfusion Units (LSPU).

The investigators will compare microvascular responses between diabetes type 1 patients with matched control-subjects.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

NONE

Enrollment

Conditions

Diabetes Mellitus Type 1

Interventions

Microvascular assessmentOTHER

Microvascular assessment

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Diabetes type 1 patients * Matched control-subjects Exclusion Criteria: * Patients or subjects with anti-inflammatory drugs

Locations (1)

University Hospital

Angers, France

Outcomes

Primary Outcomes

Neurovascular microcirculatory response

Neurovascular response will be assessed by laser speckle contrast imaging using various microvascular tests such as deionized water iontophoresis, local heating test. Results will be explained in Laser Speckle Perfusion Units (LSPU)

Time frame: one day

Data from ClinicalTrials.gov

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