Minirin Versus Oxybutynin for Nocturnal Enuresis in Children

Hormozgan University of Medical Sciences66 enrolled

Overview

Nocturnal enuresis is among the most common disorders in children. The aim of current study was to compare the efficacy and safety of Minirin and oxybutynin for treatment of nocturnal enuresis in children in Bandar Abbas in 2014.

Nocturnal enuresis is among the most common disorders in children. Several pharmacological and non-pharmacological treatments are available for nocturnal enuresis. Studies for reaching the best pharmacological treatment for this disorder are continuing. The aim of current study was to compare the efficacy and safety of Minirin and oxybutynin for treatment of nocturnal enuresis in children in Bandar Abbas in 2014.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Nocturnal Enuresis

Interventions

MinirinDRUG

Minirin 5 to 10 mg daily for 6 months

OxybutyninDRUG

Oxybutynin 5 to 10 mg daily for 6 months

Eligibility

Sex: ALLMin age: 5 YearsMax age: 14 Years

Medical Language ↔ Plain English

Inclusion Criteria: * \>5 years old * Nocturnal enuresis * Candidate for pharmacological treatment Exclusion Criteria: * Children who their parents did noted filled the informed consent form * Impossibility of follow up during the study period * History of seizure * History of rheumatologic disorders such as sjogren's disease

Locations (1)

Shahid Mohammadi hospital

Bandar Abbas, Hormozgan, Iran

Outcomes

Primary Outcomes

ّFrequency of nocturnal enuresis

Number of participants with nocturnal enuresis

Time frame: 6 months

Secondary Outcomes

Frequency of urinary incontinency

Number of participants with urinary incontinency

Time frame: 6 months

Frequency of urgency

Number of participants with urgency

Time frame: 6 months

Frequency of Xerostomia

Number of participants with Xerostomia

Time frame: 6 months

Frequency of Xerophthalmia

Number of participants with Xerophthalmia

Time frame: 6 months

Frequency of Blurred vision

Number of participants with Blurred vision

Time frame: 6 months

Frequency of Dysphagia

Number of participants with Dysphagia

Time frame: 6 months

Frequency of constipation

Number of participants with constipation

Time frame: 6 months

Frequency of Diarrhea

Number of participants with Diarrhea

Time frame: 6 months

Data from ClinicalTrials.gov

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