Impact of Omega 3 Fatty Acid Supplementation on Aromatase in Obese Subjects

Inclusion Criteria: * At least 18 years of age. * Postmenopausal as confirmed in medical history * Ability to understand the purposes and risks of the study and has signed a written informed consent form approved by the investigator's IRB (Institutional Review Board)/Ethics Committee. * Estrogen receptor positive breast cancer. Body mass index of 30 or greater. * Consented for tissue collection on CTRC (Cancer Therapy and Research Center) repository 07-32 Exclusion Criteria: * Cachexia * Active systemic illness (infection including viral illnesses such as Hepatitis and HIV) * Chronic use of NSAIDs (nonsteroidal anti-inflammatory drugs) aspirin or omega-3 free fatty acid supplementation within the last 60 days (defined as greater than or equal to 7 consecutive days) * Any NSAIDs aspirin or omega-3 free fatty acid supplementation within the last 14 days * History of medical noncompliance * Scheduled date of surgical resection that would limit the amount of time taking the intervention to less than 21 days