This is a laboratory-based research study conducted in two parts. Open cross-over design. 2 test sessions per subject included in the study. It aims at determining the postprandial blood glucose and insulin responses to the ingestion of cereal product differing by their SDS content and GI in 20 healthy non-smoking voluntary subjects, aged from 18 to 45 years.
This is a laboratory-based research study conducted in two parts. Open cross-over design. 2 test sessions per subject included in the study. It aims at determining the postprandial blood glucose and insulin responses to the ingestion of cereal product differing by their SDS content and GI in 20 healthy non-smoking voluntary subjects, aged from 18 to 45 years.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
20
Consumption of the high-SDS product (50g) alone with a glass of water
Consumption of the low-SDS product (42g) alone with a glass of water
Human Nutrition Unit, The University of Sydney
Sydney, Australia
Glycemic Response over 2 hours
iAUC of glycemia over 2 first hours of postprandial period
Time frame: 2 hours
Glycemic response
Postprandial changes in glycaemia over 3 hours (iAUC \[0-180\]), 4h (iAUC\[0-240\]), during the second part of the morning (iAUC \[120-240\] and iAUC\[180-240\]) following the intake of the test products will be analysed
Time frame: 4 hours
Blood glucose kinetic
Postprandial kinetic of glycemia over the full postprandial period (analysis time by time)
Time frame: 4 hours
Insulinemic response
Postprandial changes in insulinemia over 2 hours (iAUC \[0-120\]), 3 hours (iAUC \[0-180\]), 4h (iAUC\[0-240\]), during the second part of the morning (iAUC \[120-240\] and iAUC \[180-240\]) following the intake of the test products will be analysed.
Time frame: 4 hours
Blood insulin kinetic
Postprandial kinetic of insulinemia over the full postprandial period (analysis time by time)
Time frame: 4 hours
Blood glucose peak
Maximal concentration and delta between maximum concentration and baseline value for glycemia
Time frame: 4 hours
Blood insulin peak
Maximal concentration and delta between maximum concentration and baseline value for insulinemia
Time frame: 4 hours
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