The investigators believe sufficient spread to all nerves within the adductor canal-and thereby sufficient analgesia-can only be obtained by bolus injections and not by continuous infusions via a catheter. The aim of the study is to investigate whether an adductor canal block performed as repeated intermittent boluses provides superior pain relief to continuous infusion. The investigators hypothesize that adductor canal block performed as intermittent boluses via a catheter will reduce morphine consumption and pain as well as enhance ambulation and muscle strength compared with continuous infusion.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
110
Adductor canal block. Placed immediately postoperative. Intervention stops on POD2 12PM
Department of Anaesthesia-Surgery-Intensive Care, Gentofte Hospital
Gentofte Municipality, Hellerup, Denmark
Total opioid consumption
Difference in total opioid consumption (patient controlled analgesia pump and any potential rescue administration) between groups, from end of surgery until 12 pm on postoperative day (POD) 2.
Time frame: 2 days postoperative
Pains scores during knee flexion as assessed by the Visual analogue scale (VAS)
Visual analogue scale (VAS) pain scores (0-100 mm) during 45 degrees active knee flexion analyzed using a linear mixed model with the inclusion of all time points (Day of surgery (DOS): 8 pm, POD 1: 8 am, 12 pm, 8 pm, POD 2: 8 am and 12 pm).
Time frame: 2 days postoepratively
Pain at rest as assessed by the VAS pain scores
VAS pain scores (0-100 mm) at rest analyzed using a linear mixed model with the inclusion of all time points (DOS: 8 pm, POD 1: 8 am, 12 pm, 8 pm, POD 2: 8 am and 12 pm).
Time frame: 2 days postoperatively
Pain during the Timed Up and Go test as assessed by the VAS
Worst pain (VAS, 0-100 mm) during the Timed Up and Go test at 12 pm on POD 1 and 2.
Time frame: 1 and 2 days postoperatively
Quadriceps strength assessed as maximum voluntary isometric contraction in percentage of preoperative baseline values at 12 pm on POD 1 and 2
Quadriceps strength assessed as maximum voluntary isometric contraction in percentage of preoperative baseline values at 12 pm on POD 1 and 2.
Time frame: 1 and 2 days postoperatively
Timed Up and Go test
Time (seconds) to perform the Timed Up and Go test at 12 pm on POD 1 and 2.
Time frame: 1 and 2 days postoperatively
Number of patients able to perform the Timed Up and Go test
Number of patients able to perform the Timed Up and Go test at 12 pm on POD 1 and 2.
Time frame: 1 and 2 days postoperatively
6 min walk test
Distance ambulated (m) during the 6 min walk test performed at 12 pm on POD 1 and 2.
Time frame: 1 and 2 days postoperativley
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.