Ambulatory Blood Pressure Monitoring in Rivaroxaban Therapy

Inclusion Criteria: * Aged 18-75 years * Able to provide written, informed consent * Taking rivaroxaban for any indication within the license of the drug, both once daily and twice daily dosing can be included * Have measurable rivaroxaban levels on at least one occasion (this will be in line with standard of care, there will be no extra blood samples for the study) * Not taking concomitant medication that can affect rivaroxaban metabolism (including amiodarone, dronedarone, -azole antifungals, protease inhibitors) * On no antihypertensive or vasoactive medication * Have a baseline BP recording taken in clinic Exclusion Criteria: * Unable to provide written, informed consent * Presence of concomitant medication that may alter rivaroxaban levels and confound results (see above) * Unwilling to undergo ambulatory blood pressure monitoring * Contraindication to ambulatory blood pressure monitoring