Coagulation Disorders After Aneurysmatic Subarachnoid Haemorrhage

Tampere University Hospital32 enrolled

Overview

The main purpose of this study is to analyse the on-going coagulation process after aSAH. For investigation the investigators use the rotational thromboelastometry (ROTEM) which is a point-of-care test using a variety of activators to provide a targeted and a dynamic analysis of coagulation cascade. This is a prospective, observational clinical study done in 16 aSAH patients treated in Tampere University Hospital intensive care unit and 16 control patients (elective craniotomy due to non-ruptured intracranial aneurysm.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Aneurysmatic Subarachnoid Haemorrhage

Interventions

ROTEM analysisOTHER

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age ≥ 18 years * Acute subarachnoid haemorrhage (confirmed by computed tomography, CT, or cerebrospinal fluid erythrocyte count over 1000 x 106/l) AND confirmed origin either with computed angiography (CTA) or digital subtraction angiography (DSA) * Onset of symptoms ≤ 12 hours * Expected to stay 72 hours in the ICU Exclusion Criteria: * Pregnancy * Any long-term anticoagulant medication, except for low-dose aspirin (\<150 mg/day) * Known active cancer

Locations (1)

Tampere University Hospital

Tampere, Pirkanmaa, Finland

Outcomes

Primary Outcomes

ROTEM analysis: MCF (mm) by EXTEM activators

Time frame: 12 hours

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.