Diabetes mellitus (DM) plays an important role in the occurrence of the cerebral infarction (CI). Clinical studies have demonstrated that the CI patients with DM had a poor prognosis compared with those without DM. Previous magnetic resonance imaging (MRI) studies have shown that patients with DM had abnormalities in cerebral vessels, nerves and functions, similar with the findings in mice models. In this study, with multi-modal MRI technologies, investigators tend to observe structural and functional changes of the brain in both DM and non-DM CI patients and assess their neural rehabilitation using clinical scales in the following 6 months. Investigators also expect to find out dynamic changes of brain structure and function, to reveal the weights of factors including brain blood vessels, nerves and function remodeling related with stroke recovery, as well as the potential mechanism in CI patients with DM.
Study Type
OBSERVATIONAL
Enrollment
80
The 2nd Affiliated Hospital of Zhejiang University, School of Medicine,
Hangzhou, Zhejiang, China
RECRUITINGmodified Rankin scale (mRS)
scores range from 0 (no symptoms) to 6 (dead)
Time frame: 6 months
National Institute of Health Stroke Score
scores ranging from 0 to 42 (the higher the score, the greater the function deficits)
Time frame: 6 months
Barthel index
score ranging from 0 (totally dependent) to 100 (completely independent)
Time frame: 6 months
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