Breast cancer are common on mediterranean basin. Epidemiological data suggest that breast cancer in young women (\< 40years old) is more aggressive in the Maghreb countries comparatively to western countries. This aggressiveness could be associated with phenotypic and genotypic differences between this two populations.
The object of this study is to compare the genotypic and phenotypic differences between south and north shore of the mediterranean sea.
Study Type
OBSERVATIONAL
Enrollment
460
CHU de Montpellier
Montpellier, France
Genetic analysis of Breast Cancer susceptibility gene 1 (BRCA 1)
Time frame: The day of inclusion
Genetic analysis of Breast Cancer susceptibility gene 2 (BRCA 2)
Time frame: The day of inclusion
Analysis TNM grade
Tumors will be phenotyped by giving the histological characteristics (TNM and SBR grade, hormone receptors (ER, PR), growth factors (Ki 67) and HER2)
Time frame: The day of inclusion
Analysis histoprognostic grade Scarf Bloom and Richardson (SBR)
Tumors will be phenotyped by giving the histological characteristics (TNM and SBR grade, hormone receptors (ER, PR), growth factors (Ki 67) and HER2)
Time frame: The day of inclusion
analysis of hormone receptor ER
Tumors will be phenotyped by giving the histological characteristics (TNM and SBR grade, hormone receptors (ER, PR), growth factors (Ki 67) and HER2)
Time frame: The day of inclusion
growth factors analysis (Ki 67)
Tumors will be phenotyped by giving the histological characteristics (TNM and SBR grade, hormone receptors (ER, PR), growth factors (Ki 67) and HER2)
Time frame: The day of inclusion
analysis of HER2
Tumors will be phenotyped by giving the histological characteristics (TNM and SBR grade, hormone receptors (ER, PR), growth factors (Ki 67) and HER2)
Time frame: The day of inclusion
analysis of hormone receptor PR
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Tumors will be phenotyped by giving the histological characteristics (TNM and SBR grade, hormone receptors (ER, PR), growth factors (Ki 67) and HER2)
Time frame: The day of inclusion