Monteleukast Versus Inhaled Mometasone for Treatment of Otitis Media With Effusion in Children

Hormozgan University of Medical Sciences143 enrolled

Overview

Otitis media is one of the most common infections among children and is a complication in about 30% of common colds. The most common complication of acute otitis media is otitis media with effusion. Some studies have reported the effects of montelukast and mometasone nasal spray in treatment of otitis media with effusion. However, current information is inadequate in this issue. The aim of this study was to compare the effectiveness of montelukast and mometasone nasal spray in treatment of otitis media with effusion in children attending Koodakan hospital in Bandar Abbas, Iran.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

143

Conditions

Otitis Media With Effiusion

Interventions

Eligibility

Sex: ALLMin age: 2 YearsMax age: 6 Years

Medical Language ↔ Plain English

Inclusion Criteria: * • Children who were between 2 to 6 years old * Definite diagnosis of OME with symptoms and examination Exclusion Criteria: * • Currently were using corticosteroids or prophylactic monteleukast * Chronic pulmonary or cardiac diseases or immune deficiency * Allergic rhinitis * Hypersensitivity to monteleukast or corticosteroids * Avoidance of parents to fill the written informed consent

Outcomes

Primary Outcomes

Treatment response

Defined as complete, partial, or no response based on the physician examination

Time frame: 1 months

Secondary Outcomes

Drug side effects

Frequency of Drug side effects as reported by the children or their parents

Time frame: 1 month