This study evaluates the incidence of hepatic encephalopathy between covered stent of diameter of 7mm and 8mm in TIPS(transjugular intrahepatic portosystemic stent shunt ).Half of the participants will receive stent of diameter of 7mm ,while the other half will receive stent of diameter of 8mm.
TIPS is effective in the treatment of hemorrhage of digestive tract and intractable ascites,which are the complications of cirrhosis. At present, the high incidence of hepatic encephalopathy has been a major problem after TIPS. The high incidence rate of hepatic encephalopathy was closly associated with the diameter of the stent. We often use the stent of diameter 8mm in TIPS.In this study, we try to use the stent of smaller diameter of 7mm in TIPS,and compare the incidence of hepatic encephalopathy between the stent of diameter of 7mm and 8mm .
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
216
108 patients use the stent of diameter of 7mm in TIPS
108 patients use the stent of diameter of 8mm in TIPS
The incidence of hepatic encephalopathy after TIPS
The incidence of hepatic encephalopathy after TIPS in 7day,1,3,6,12month
Time frame: 1 year
the incidence of shunt restenosis after TIPS
The incidence of shunt restenosis after TIPS in 7day,1,3,6,12month
Time frame: 1 year
the recurrence rate of gastrointestinal bleeding after TIPS
The recurrence rate of gastrointestinal bleeding after TIPS in 7day,1,3,6,12month
Time frame: 1 year
Portal venous pressure before and afterTIPS
Portal venous pressure before and afterTIPS.
Time frame: 1 year
liver function in different periods
liver function during different periods before and after TIPS in 7day,1,3,6,12month
Time frame: 1 year
blood ammonia in different periods
blood ammonia before and after TIPS in 7day,1,3,6,12month
Time frame: 1 year
jaundice index in different periods
jaundice index before and after TIPS in 7day,1,3,6,12month
Time frame: 1 year
platelet count in different periods
platelet count before and after TIPS in 7day,1,3,6,12month
Time frame: 1 year
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.